The combination of Atazanavir Ritonavir was approved for use in India in 2012. It is on the World Health Organization's List of Essential Medicines, the effective as well as safest medicines required in a health system.
Atazanavir, typically administered with the low-dose of ritonavir (atazanavir/r). This combination has been an important innovation for the perspective of treatment of adult HIV infection owing to its ease of dosing, minimal toxicity, high genetic barrier to resistance, virologic potency, favorable resistance profile. Additionally, this combined drug has the lower effect on the lipid as well as glucose metabolism. There are some important potential limitations in order to the treatment with atazanavir/ritonavir such as interactions with acid-reducing agents and those mediated by low-dose ritonavir, benign hyperbilirubinemia with jaundice and a rare risk of nephrolithiasis. The formulation of Atazanavir Ritonavir tablets 300mg/100mg (ATV/r) for treatment of HIV-1 infection among adults living with HIV/AIDS in both the WHO Essential Medicines List and the WHO Essential Medicines List for Adults. The principal reasons for requesting this inclusion are as follows:
The recommended oral dose of Atazanavir 300mg /ritonavir 100 mg tablets for adolescents and adults is one tablet daily, in combination with other antiretroviral agents. ATV/r 300mg/100mg tablets should be taken with food. Side Effects: Side effects generally appear minimal. They may include headache, abdominal pain, diarrhea, yellowish skin and muscle pains. Extreme care is required in such people who are with underlying liver problems. The use of this HIV medication in pregnancy appears to be safe. In the combination of atazanavir and ritonavir, atazanavir functions as a protease inhibitor and ritonavir works in order to enhance the levels of atazanavir. Check the detailed side effects of Atazanavir and Ritonavir tablets
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3/26/2022 04:12:23 am
Great! Thank you for sharing this informative content.
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