Prescribing information (PI): "For full information read PI" and consult a Physician before initiating any treatment.
Indication: It belongs to the thalidomide analog class that was used in the treatment of: Multiple myeloma: Lenalidomide 25 mg drug is used in the treatment of Myeloma when combined with dexamethasone in a patient who has at least received one prior therapy. Certain researchers show that Lenalidomide binds myeloma cells called cereblon. This binding causes myeloma cell death. Transfusion dependent anemia: Patients suffering from myelodysplastic syndromes (MDS) with or without additional cytogenetic abnormality are treated with this particular drug. Mantle cell lymphoma: Lenalidomide for multiple myeloma drug is used to treat Mantle cell lymphoma patients who have at least received two prior therapy one of which must be bortezomib. Dosage and Administration: This drug is available in capsule form of concentration 2.5mg, 5mg, 10mg, 15mg, 20mg, and 25 mg. This capsule is taken orally with water. Do not chew, crush, or break lenalidomide capsules. The capsule should be stored at 59 to 86°F (15 to 30°C). Different doses of the drug are administered according to the doctor's prescription. However, the standard dose is: Multiple myeloma: The highest recommended dose of this drug in multiple myeloma is 25mg daily taken orally for 21 days. This drug comes under the maintenance therapy drug that increases 41% survival rate. Treatment is modified or discontinued according to clinical trials. Multiple myeloma followed by stem cell transplantation: 10mg daily dose of lenalidomide is used in a patient who have recently gone through stem cell transplantation suffering from multiple myeloma. Myelodysplastic syndromes: 10 mg drug is orally consumed daily after clinical and laboratory findings. This dose of lenalidomide is used for the treatment until there is no accepted toxicity. If the patient experiences thrombocytopenia and neutropenia then the dose of medicine is adjusted accordingly. Mantle cell lymphoma: 25mg drug for about 28 days is orally taken daily until no accepted toxicity. The dose of this medication is taken according to the reports based on blood count. Missed Dose: If any dose of this drug is missed then take that dose as soon as you remember. Do not take two doses at the same time as it can cause an overdose. Overdose: If this medicine is taken in a high dose then the patient should immediately consult a doctor and poison control center. Precaution: Do not open or break the capsule. Handle this capsule with more care. If the medicine is broken and any area is exposed then immediately wash with soap and water. Contraindication: Do not use this specific drug during pregnancy. Thalidomide may cause limb abnormalities. If this drug is used during pregnancy it may cause birth defects or fetus damage. To avoid any fetal damage from lenalidomide this drug should only be distributed under, "Revlimid REMS”. Read:- Side effects of Lenalidomide
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