As an inorganic compound and drug arsenic trioxide comes under the brand name trisenox, which is prescribed in order to treat cancer of the blood and bone marrow known as acute promyelocytic leukemia (APL). It may also be recommended to be used together with another drug named tretinoin. How you have arsenic trioxide: The trisenox is given by injection into a vein by a doctor over 2 hours, usually once in a day or as instructed by a healthcare practitioner. The injection should be injected quite slowly (e.g., over 4 hours) in case patients have a reaction to the medicine such as flushing, dizziness, and fast heartbeat. Mechanism of Action: The mechanism of action of this medication is not completely clear, but it is believed to appear in order to cause cancerous cells to self-destruct. This is named programmed cell death or apoptosis, a specific natural process of self-destruction. The arsenic trioxide prevents the cancer cells from multiplying and can keep cancer cells from being supplied with necessary nutrients that are involved in feeding their growth. Side effects of Arsenic Trioxide: The most commonly occurred arsenic trioxide side effects are listed as follows:
What is the most crucial information I must know about arsenic trioxide? The trisenox may cause fatal complications by changing the mechanism of the immune system. Contact your healthcare practitioner immediately if you're struggling with a fever, weight gain, swelling, pain while breathing, increased heart rate, or feeling like you might pass out. The arsenic trioxide uses are responsible for causing a serious heart problem. You're comparatively at increased risk if you're using certain other drugs. Interact with your healthcare team about all medications you're taking currently. Ask for emergency medical assistance if you have increased heartbeats, fluttering in the chest, sudden dizziness and shortness of breath. What may interact with this medicine? Do not take arsenic trioxide injection with any of the following medicines:
Arsenic trioxide may affect the fertility in male patients. Although, it is crucial to consider birth control in order to prevent pregnancy because this agent may harm the unborn baby in case a pregnancy does occur. Breastfeed needs to be avoided while receiving it, and for minimum 14 days after the last dose. What happens in case of overdose of arsenic trioxide? In case you or someone else may have overdosed on trisenox, call your healthcare practitioner or the Poison Control center. What happens in case of missed dose? It is absolutely necessary not to forget your required dose. Get in touch with your healthcare practitioner if you are not able to keep an appointment. Where should I keep my medicine? Store trisenox at controlled room temperature (15°C to 30°C). Unused portions of every vial need to be discarded precisely. Avoid saving any unused portions for later administration. How much does arsenic trioxide cost? The arsenic trioxide price may vary from branded to generic (non-branded) drugs. The price of a single vial of 10 mL injection may range from 412 INR to 818 INR. NOTE: The information provided in this article is only for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis, of a qualified healthcare practitioner.
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